LL-37 (5mg)
Description & mechanism
LL-37 is the C-terminal antimicrobial peptide of human cathelicidin (hCAP-18). It is used in research to study antimicrobial-peptide activity, membrane interactions, and immunomodulatory signalling in cell-free and cell-culture systems.
Applications in research
- Antibacterial and antifungal activity and membrane-disruption assays
- Biofilm and host-defence interaction studies
- Immunomodulatory (chemokine/cytokine) signalling in cell culture
Specifications
Handling, reconstitution & storage
Reconstitute the lyophilized solid in sterile water or bacteriostatic diluent to the desired working concentration; mix by gentle inversion and avoid vigorous agitation or repeated freeze-thaw. Sterile-filter (0.22 µm) if aseptic use is required, aliquot into single-use volumes, and store reconstituted material frozen at -20 °C.
Precautions & notes
For in-vitro research and laboratory use only. Bodily introduction of any kind into humans or animals is strictly forbidden. Handle as a bioactive substance using appropriate PPE and consult the safety data sheet.
References
This product is furnished for in-vitro research and laboratory use only. Bodily introduction of any kind into humans or animals is strictly forbidden.